![]() ![]() The SLC6 NTTs are widely expressed in the mammalian brain and play an essential role in regulating neurotransmitter signaling and homeostasis by mediating uptake of released neurotransmitters from the extracellular space into neurons and glial cells. Wright said.The neurotransmitter transporters (NTTs) belonging to the solute carrier 6 (SLC6) gene family (also referred to as the neurotransmitter-sodium-symporter family or Na(+)/Cl(-)-dependent transporters) comprise a group of nine sodium- and chloride-dependent plasma membrane transporters for the monoamine neurotransmitters serotonin (5-hydroxytryptamine), dopamine, and norepinephrine, and the amino acid neurotransmitters GABA and glycine. “An overall plan to improve health and long life would be a Mediterranean diet or MIND diet that delivers antioxidants with fruits, vegetables, healthy oils, fish and whole grains,” Dr. ![]() The experts who spoke with MNT say the best way to slow down the aging process through nutrition is to follow a healthy and well-balanced diet. Taurine naturally occurs in the human body and a deficiency of taurine in humans is rare. So yes, what we eat definitely makes an impact,” Dr. vitamin A or iron) can lead to shorter lifespans and we also know very unhealthy highly processed and high-meat diets lower longevity by increasing the risk for chronic conditions like type 2 diabetes, heart disease and stroke. “We also know that certain vitamin or mineral deficiencies (ie. We know physical activity increases longevity,”ĭana Hunnes, PhD, a senior clinical dietitian at the UCLA Medical Center in Los Angeles, told MNT. But, many animal studies show that a slight caloric deficit increases longevity. It really depends on what the nutrient is and if it’s an overall diet quality factor. “Diet and certain deficiencies can impact longevity through various mechanisms. ![]() Nutrition and diet are just some of the factors believed to speed up or slow down aging. Human aging is a growing area of researchĪnti-aging and promoting longevity is a growing body of research. Similar positive benefits were also seen in monkeys who were given taurine. They had increased energy expenditure, an increase in bone mass, reductions in depression and anxiety-like behaviors, improved muscle strength and endurance, and a reduction of insulin resistance. The researchers also reported that the animals who were given taurine for a year were healthier across almost all measures when compared with the other group. This equated to roughly seven to eight human years, or three to four months in mice years. The mice that were given taurine had an increased lifespan of 12% in females and 10% in males. Each day the mice were either given taurine or a control solution. ![]() The researchers examined 250 mice who were roughly 45 years of age in human terms. “That’s when we started to ask if taurine deficiency is a driver of the aging process, and we set up a large experiment with mice,” Yadav said. In humans, they found that taurine levels in 60-year-olds were only a third of those found in 5-year-olds. In undertaking their study, the researchers first examined the levels of taurine in the blood of monkeys, mice and people and discovered that levels decrease significantly with age. ![]()
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